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Neutrophil to Lymphocyte Ratio Calculator (NLR)

Neutrophil to Lymphocyte Ratio (NLR) = Absolute Neutrophil count / Absolute Lymphocyte count
Indicator of inflammation (infection) and physiologic stress (e.g., hypovolemic shock)








Physiologic stress level
– NLR < 3 : Normal
– NLR 3 ~ 6 : Borderline
– NLR 6 ~ 9 : Mild stress
– NLR 9 ~ 18 : Moderate stress
– NLR > 18 : Severe stress

Neutrophil to Lymphocyte Ratio (NLR) equation :

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Effect of physiologic stress on NLR :

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NLR Pitfalls:

  • NLR may increase with exogenous steroid use.
  • Cell counts may vary in situations such as leukemia, chemotherapy, and G-CSF use.
  • In HIV patients, baseline NLR may be increased.

Reference : PulmCrit (https://emcrit.org/pulmcrit/nlr/)

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