mDF Calculator (modified Discriminant Function)

Maddrey’s Discriminant Function
A calculator to predict the severity and short-term prognosis of Alcoholic hepatitis patients.
mDF = 4.6 x (PT[patient](s) – PT[control](s)) + Total bilirubin (mg/dL)

Total Bilirubin (mg/dL) :
PT[Patient] (second) :
PT[Control] (second) :

mDF < 32 : Moderate alcoholic hepatitis
mDF ≥ 32 : Severe alcoholic hepatitis

Reference :
Maddrey WC, Boitnott JK, Bedine MS, Weber FL Jr, Mezey E, White RI Jr. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology. 1978 Aug;75(2):193-9. PMID: 352788.