Medical Calculator – SonDoctor.com
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HUGE (Hematocrit + Blood urea + GEnder) Calculator
This calculator helps differentiate between normal aging kidney and chronic kidney disease (CKD) in patients over 70 using the HUGE formula:
L = 2.505458 – [0.264418 x Hct] + [0.118100 x Urea] [+ 1.383960 if male]
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L ＜ 0 : Suggests Normal aging kidney
L ≥ 0 : Suggests Chronic kidney disease
Reference :
Alvarez-Gregori JA, Robles NR, Mena C, Ardanuy R, Jauregui R, Macas-Nu Nunez JF. The value of a formula including haematocrit, blood urea and gender (HUGE) as a screening test for chronic renal insufficiency. J Nutr Health Aging. 2011 Jun;15(6):480-4. doi: 10.1007/s12603-011-0001-0. PMID: 21623470.
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