Albumin to Globulin (A/G) Ratio Calculator

A/G ratio = Albumin / (Total protein – Albumin)
Calculated globulin = Total protein – Albumin

Normally, albumin is slightly higher than globulin, so A/G ratio is slightly over 1. When A/G ratio is less than 1, it is referred to as a reversed A/G ratio.

A/G ratio less than 1 (Reversed A/G ratio)
1. Increased globulin production:
– Polyclonal gammopathy (inflammation, autoimmune disorders)
– Monoclonal gammopathy (myeloma)
2. Decreased albumin production or loss:
– Liver cirrhosis, nephrotic syndrome

A/G ratio greater than 2.5
1. Dehydration (concentration of albumin due to hemoconcentration)
2. Leukemia (reduced globulin production)
3. Immunodeficiency (e.g., HIV, congenital disorders)